Correlation of Plasma Interleukin 1 Levels with Disease Activity
in Rheumatoid Arthritis with and without Ozone
Augusta-Klinik, 55543 Bad Kreuznach, Germany.
The mean plasma level of interleukin 1 beta was significantly
higher in 51 patients with rheumatoid arthritis (RA) than in 21
rheumatoid arthritis patients treated with ozone, as control group
of similar age in both groups. Plasma IL-1 beta correlated
positively with Ritchie joint index, pain score, and erythrocyte
sedimentation rate and correlated negatively with haemoglobin
concentration. These results support the idea that IL-1 beta has a
central role in the phatogenesis of RA and the ozone has
influenced in the concentration level of IL-1 beta.
Source: 2nd International Symposium on Ozone Applications
Havana, Cuba – Mach 24-26, 1997.