A number of medical professionals and researchers strongly believe that this gas can bring about various therapeutic advantages. Ozone therapy has been used and thoroughly examined for over a century. Its impacts to health have been proven to be safe and produce minimal and highly minor inevitable side effects. Medical ozone is being utilized in the treatment of diseases. It works by deactivating bacteria, fungi, protozoa, and yeast. It also fuels oxygen metabolism and boosts the immune system. While it is uncommon to be using medications in gaseous form, it is for this very purpose that special application procedures have had to be established for the nontoxic use of medical ozone. In procedures applied locally such as in the case of external wound treatment, a transcutaneous ozone gas bath application has been developed and recognized as one of the most practical and useful techniques.