AU  - Bocci V

TI  - Biological and clinical effects of ozone. Has ozone therapy
      a future in medicine?

AB  - Although ozone therapy has been used as an alternative 
      medical approach for four decades, it has encountered scepticism,
      if not outright objection, by orthodox medicine. This prejudice 
      is not unjustified because ozone therapy often has been 
      used without rational basis or appropriate controls. With 
      the advent of precise medical ozone generators, it is now 
      possible to evaluate some mechanisms of action and possible 
      toxicity. In contrast with the respiratory tract, human 
      blood exposed to appropriate ozone concentrations is able 
      to tame its strong oxidant properties and neither acute 
      nor chronic side effects have ensued in millions of patients 
      treated with ozonated autohaemotherapy. This paper summarises 
      studies aimed at clarifying biological effects, defining 
      any possible damage, the therapeutic window, and suitable 
      doses able to express therapeutic activity. Although an 
      unfashionable and unpopular approach, it is hoped that 
      orthodox medicine will help to critically assess the validity 
      of ozone therapy.

MH  - Oxidants, Photochemical|AE/*TU
MH  - Ozone|AE/*TU
SO  - Br J Biomed Sci 1999; 56(4):270-9
DP  - 1999
TA  - Br J Biomed Sci
PG  - 270-9
IP  - 4
VI  - 56
UI  - 20255935