AU  - Rosc D
AU  - Ponikowska I
AU  - Paczuski R
AU  - WÖodarczyk K
AU  - Zastawna E
AU  - Michalski A
TI  - [The influence of ozone therapy on endothelial damage markers 
      in patients with atherosclerosis of lower extremities]
AB  - The aim of study was to evaluate the influence of the treatment 
      with oxygen-ozone mixture on the blood plasma antigen concentration 
      of tissue plasminogen activator (t-PA) and von Willebrand 
      factor (vWF) in patients suffering from atherosclerotic 
      disease of lower extremities. The study was performed in 
      the group of 28 (M/F 22/6) patients means aged 64.1 years 
      with atherosclerotic diseases of lower extremities, in 
      whom 2 weeks therapy with oxygen-ozone mixture was used.
      The control group consisted of 30 healthy volunteers in 
      mean age 51.0 years. In the blood plasma obtained from 
      the patients before and after treatment with oxygen-ozone 
      mixture and from the control group determinations of t-
      PA and vWF antigen using ELISA were done. Both parameters
      were significantly increased in the patients before the 
      treatment in comparison to the healthy controls. The treatment 
      with oxygen-ozone therapy caused in patients slight statistically 
      not significant raise of t-PA and vWF antigen showing the 
      endothelial stimulation but not the destruction of vascular 
      endothelium.

SO  - Pol Merkuriusz Lek 1999 Mar; 6(33):135-7
DP  - 1999 Mar
TA  - Pol Merkuriusz Lek
PG  - 135-7
UI  - 99293931