OxyFile #562
Biochemical Safety Control in Ozonetherapy Kontorschikova C.N. Medical Academy Nizhni Novgorod, Russia Abstract: The use of ozone in medicine as well as elaboration of new approaches require due control on safety. It should be considered that according to the concentration ozone can: 1. present acertain threat for the intensification of free-radical reactions 2. to maintain dynamic balance of pro- and antioxidant systems of the organism responsible for the regulation of the membrane structure and metabolism. The results of our experiments in vivo and vitro made it possible to assess chemoluminescence, molecular products of lipidperoxidation, general antioxidant activity and to suggest then to be used as control methods. Efficiency of these methods was confirmed by ozonetherapy in different pathologies. Date: 1995