OxyFile #558
Ozonetherapy in Out-Patient Dermatological Practice Sergei L. Krivatkin, Alexander L. Gromov, Elena V. Krivatkina Sormovo Interdistrict Dermatovenereological Dispensary Nizkny Novgorod, Russia Abstract: Ozonetherapy being used in different fields of medicine is not successfully applied in out-patient dermatological practice. Therapeutical results of ozonetherapy in acne, alopecia, drug eruptions, eczema, herpes, lichen planus, neurodermitis, prurigo, psoriasis and psoriatic arthritis, pyoderma, scleroderma, tinea pedis and venous leg ulcers, 350 patients in all, are demonstrated. It is estimated that ozonetherapy is effective, safe, inexpensive, easy to use, considered that it is worthy to be used in out-patient dermatological practice. Dermatology differs from other clinical disciplines by its various capabilities of observing diseases (about 2000 dermatoses), considerable percent of chronic diseases and the deficiency of high effective therapeutical approaches. Naturally, the search of new promising curative directions is of great importance. Taking into consideration the broad spectrum of ozone interactions in the human body (bactericidal, fungicidal, analgesic, antiinflammatory, immunocorrective, microcirculation stimulating, detoxicating, wounds healing, etc.) and the positive experience of ozonetherapy (OT) application in very different fields of medicine, we decided to use it in our out-patient dermatological practice, having some theoretical basis and proposing to receive the positive therapeutical results in concrete dermatoses. 350 patients suffering from acne and rosacea (n=60) alopecia (17), drug eruptions (3), eczema (52), herpes (70), lichen planus (14), neurodermitis (22), prurigo (2), psoriasis (27) and psoriatic arthritis (8), pyoderma (47), scleroderma (4), tinea pedis (15) and venous leg ulcers (10) were included in this study. Six standard forms of OT were used: AHT min, techniques with the use of plastic bag, intramuscular injections, ozonized olive oil and water. The first two of them were applied more often: AHT min almost in all the patients and plastic bag techniques in the patients with external exudative manifestations. As usual OT was carried out as the only therapeutical method or in combination with very simple external routine medicines. Only in neurodermitis, prurigo and psoriatic arthritis we consider always worthy to combine OT with other special internal treatment. As a source of O2/O3 mixture the home ozonizer was used (concentration of O3 7-20 mcg/ml). Laboratory control was realized by means of available bacteriological, biochemical, clinical, immunological and roentgenological examinations. Date: 1995