OxyFile #439
Treatment of Hepatitis C with Intravenous Hydrogen Peroxide Report of One Case This is the report of a case of hepatitis c in a 38 y/o white male air conditioning-heater repairman and the response to intravenous hydrogen peroxide therapy. The patients laboratory findings went from origionally grossly abnormal to entirely normal after a dozen iv hydrogen peroxide treatments over a ten month time-span. His symptoms of fatigue, anorexia and weight loss resolved and he returned to work after the fourth treatment. One year after initiating treatment the patient is free of symptoms, feels well and is at work full time. History & Physical 9/5/95 Medical history is essentially non contributory, having a positive history for the usual childhood diseases without sequalae and having no serious adult illnesses or injuries. Present Illness: The patient began having nausea, weakness, fatigue and anorexia about 3 months prior to being seen in our office. There was no history of significant weight loss, or of jaundice. Physical Exam: Complete physical exam was negative, there being no physical findings relating to any organ-system disease. Laboratory data: 9/5/95 CBC WBC 7300 Neut. 41.6 RBC 5.32 million Lymph 43 (atypical) Hgb 16.3 Mono 15.4 Hct 48.6 Plat. 195 thou. Chemistry profile was within normal limits (24 tests) An intravenous infusion of hydrogen peroxide was given 9/8/95 without any untoward effects. By 9/10/95 the patient reported a slight worsening of his symptoms of fatigue and nausea. It was felt that these symptoms might well be due to a Herxheimer effect. Blood work was repeated at this time. CBC WBC 13,300 Neut. 8 bands 9 RBC 5.2 mil Lymph 79 64% atyp. Hbg 15.5 Mono 3 HCT 47 Baso 1 2 nucleated RBC Plat 199 thou. ESR 10 mm/hr Chemistry: PT 13 AST 50 hi n 15-37 PTT 27 ALT 79 hi n 30-65 Mono test neg A/G 0.96 n 1.1-2.2 CRP pos LDH 281 n 100-193 RA Pos CK 20 lo n 21-215 Hep C antibody reactive Intravenous Hydrogen Peroxide IVs were given on 9/11, 9/13 and 9/15/95, which were all tolerated well. Lab data 9/17/95 CBC WBC 10,300 Neut. 24.7 RBC 4.7 mil Lymph 60.5 30% atyp Hgb 14.0 Mono 10.2 HCT 42 Eos 4.3 Plat 250 thou. Baso 0.3 Chem. A/G 0.9 lo LDH 215 hi Hepatitis C Reactive Mono test neg An iv of 250 D5W with Vit C 5Gm Dexpanthenol 5cc, pyridoxine2cc, B complex 2cc and B-12 2cc was given 9/20. IVs of hydrogen peroxide were given 9/25, 9/27, and 10/2. Vitamin IVs were given 10/4, 10/6 and 10/9. Lab data 11/20/95 CBC WBC 9,100 Neut. 53.6 RBC 4.47 mil Lymph 32.6 none atyp Hgb 14.2 Mono 9.0 HCT 41.0 Eos 4.5 Plat 218 thou. Baso 0.3 Chem ALB 3.3 lo (n 3.4-5.0) A/G 0.9 lo (n 1.1-2.2) AST 49 hi (N 15-37) ALT 88 hi (n 30-65) Hydrogen peroxide iv was given 10/11/95 and vit IVs given 3/27 and 3/29/95. By this time the patient was feeling well, wwas back to work full time and was keeping his appointments in a rather haphazard manner. Lab data 2/6/96 CBC Normal cbc Hepatitis C test Pos. Chem. LDH 127 n 100-190 TP 7.2 n 6.4-8.2 Glob 3.5 A/G 1.1 ALB 3.7 ALP 69 Tot bil 0.22 AST 32 ALT 61 SGT 32 Lab data 3/25/96 CBC WBC 10,500 Neut. 53 1 band RBC 4.69 mil Lymph 30 rare atyp. HGB 14.6 Mono 13 HCT 45 Eos 4 Chem LDH 94 Glu 116 All other chemistries were within the normal range (22 tests) Lab data 7/31/96 CBC WBC 7500 Neut 44 1 band RBC 4.43 mil Lymph 49 0 atyp Chem. Chemistry profile normal This patient was last seen in the office march 1996, he is in good health, feels well and has no complaints. The Hydrogen Peroxide IVs consisted of 0.03% H202 mixed by giving 2.5cc of 3% H202 in 250cc D5W, with 1.5 cc NaHC03 added. The IVs were infused over 2 hrs. Author: Ronald M. Davis, M.D. 5002 Todville, Seabrook, TX 77586