OxyFile #192
UI - 91305347
AU - Priimak AA
AU - Kaliuk AN
AU - Kirgintsev AG
TI - [The effect of an ozone-oxygen mixture on Mycobacterium
tuberculosis and conditionally pathogenic microorganisms]
AB - The impact of a gaseous ozone-oxygen mixture (OOM) on
Mycobacterium tuberculosis (MBT) and opportunistic microorganisms
was studied. It was demonstrated that on 15- and 30-min exposure,
OOM caused a significant decrease in the number of colonies of
the grown microorganisms as compared with the control. The OOM
mixture produced the highest effect of the MBT suspension, which
is likely to be related to a greater surface of ozone contact
with a cell than with a dense medium, and higher concentration of
ozone and its highly active radicals that arise from a treatment
process. After treatment with a gaseous mixture, 80-90% of the
microbial cells lost their reproductive ability. The strains
grown after OOM action retain drug sensitivity of the original
strain. The results suggest that the use of a gaseous OOM mixture
is promising in the treatment of tuberculosis to cleanse the
destruction cavities and pleural empyemas, including those of
nonspecific etiology.
PT - JOURNAL ARTICLE
LA - Rus
SO - Probl Tuberk 1991;(4):7-10