OxyFile #181
UI - 94076986
AU - Fish J
AU - Healy J
AU - Gensure R
AU - Choe E
AU - Ferrara J
TI - Effect of peritoneal and gastric irrigation with ozonated saline
on arterial and venous blood gas values.
AD - Department of Surgery, Tulane University School of Medicine, New
Orleans, LA 70112.
AB - Ozone, a proven in vitro antiseptic agent, has been shown in vivo
to reduce infectious morbidity when used as a lavage solution in
rodent fecal peritonitis. As concern that absorption of hydroxyl
radical byproducts of ozone breakdown might be deleterious to
blood buffering capacity, the effects of a 5 minute intragastric
or peritoneal lavage with ozonated saline on rodent arterial and
venous blood gas values were determined. Compared to values
obtained following lavage with oxygenated saline or normal
saline, ozonated saline irrigation produced no appreciable
alterations in arterial or venous pH, pO2, and pCO2 over a 1 hour
observation period. Short-term ozonated saline peritoneal lavage
does not appreciably effect rodent blood buffering capacity.
PT - JOURNAL ARTICLE
LA - Eng
SO - Life Sci 1993;53(25):1867-72