OxyFile #128
Canadian Medical Research Mystery
DOD Positive Ozone / HIV Results Ignored
C. 1994 by Ed McCabe,
nvestigative Reporter, and author of the bestseller
"Oxygen Therapies"
Non-Profit Reproduction Encouraged
Commercial Reproduction Encouraged
With permission please.
The story of a mystery within the modern Canadian Medical
Establishment. A proven safe and effective treatment for alleviating
AIDS symptoms is being hidden from view.
Summary: Various Canadian government and military and commercial
representatives got together in 1989-1990 to allegedly test the safety
and effectiveness of "ozone therapy" in the treatment of AIDS. Two
small pilot studies were undertaken. This resulted in the 1991
Publication: The use of ozone-treated blood in the therapy of HIV
infection and immune disease - a small pilot study (phase 1 was 10
patients, phase 2 was 14 patients) of medical ozone's safety and
efficacy. "AIDS" 5:981-984. G. Garber, D Cameron, N Hawley-Foss, D
Greenway and M. Shannon(1). The methods used were antiquated, and the
device quality control was non-existent by any objective standard, and
the actual published conclusions were exactly opposite to the
conclusions written up by one of the chief investigators.
This is a study the rare detractors of medical ozone like to quote, to
falsely try and promote a viewpoint that it doesn't work. I say
falsely, because we know for a fact that such detractors parade the
false published version of this study out instantly, while hundreds of
positive medical ozone references held in their possession remain
strangely ignored. Hundreds of references were sent to one of them,
the U.S. FDA, and they have admitted having them - in writing, yet
they never mention them.
Modern Medical Ozone therapy consists of taking three combined very
active atoms of pure oxygen (ozone) and surrounding all the anaerobic
(can't live in oxygen) primitive cell bacteria, viruses, funguses and
parasites with it. This active form of pure oxygen makes it
impossible for the quickly oxidized microbes to live, and ozone is
also harmless to normal healthy human cells when used correctly. All
the secondary infections, and possibly even the prime infection either
go away, or enter a level of remission concurrent with the procedures
and methods applied, including the pre-treatment health of the
patient. When applied properly, meaning using correct procedures,
delivery methods, concentrations, volumes, and durations, ozone is
extremely safe and effective, according to published animal and human
studies over the past one hundred years (2,3,4).
In an early (early for North American research), Canadian
establishment attempt to see if there is any validity to the
overwhelmingly positive reports on medical ozone coming out of Europe,
and, to see if it was safe, an outdated and poorly executed ozone
protocol was used in a "small pilot" study by researchers
inexperienced in the use of ozone therapies. Outdated because the
method chosen was deemed painful and ineffective in 1938(5), and
inexperienced, because they had never used ozone before.
Modern medical ozone application has a few significant procedures that
classically trained scientists outside the field know nothing about,
since the many ozone therapy procedures are not taught in North
American and Canadian medical schools. These investigators incorrectly
chose the delivery method of minor autohemotherapy as their starting
point. This was a backwards decision when we consider that ozone has
been in use by thousands of European physicians for over 50 years, and
far better methods are currently in use worldwide. The minor
autohemotherapy method (min AH) they chose involved withdrawing a
small amount of blood, mixing ozone into it - to kill the viruses, and
then re-injecting the dead viruses - this is the immunization theory.
Minor autohemotherapy is a poor cousin to major autohemotherapy, which
is itself now giving ground to even more successful modern delivery
methods.
The most modern of the successful ozone therapies skip this unneeded
dead virus inoculation step, and directly flood the blood, lymph, and
cells with virus destroying pure medical ozone gas. This is done in a
variety of ways, IV, dialysis type recirculatory systems, ear,
vaginal, penile, and rectal insufflation, sauna bags and devices,
breathing ozonated air, and drinking ozonated water. Our bodies soak
it right up harmlessly because we evolved in an oxygen environment.
Starting in the late 1800's up to the present, hundreds of thousands,
perhaps millions use some of these methods daily.
The small pilot trial we are discussing was sponsored by the Ottawa
General Hospital Infectious Disease Division, the Canadian Department
of Health and Welfare, the Canadian Federal Center For AIDS, the
Canadian Department Of National Defence, and The Meuller Medical
Company of Canada, now Vas-O-Gen.
My analysis: If you compare the protocols used in this study with the
known to be more effective modern ozone methods, and then also compare
the internal letters of the investigators reporting their documented
findings against the final published version of the study, it
immediately becomes apparent that the published study was, if not
fraudulent, then close to it. How can I make such an accusation? Let's
look closely at the facts.
Of prime importance is the fact that the very design of the study was
so out of touch with current known worldwide private ozone medical
practices that it should never be labeled "ozone therapy." It is a
travesty to call it anything other than a poor distant cousin to
modern ozone therapy.
However, on the plus side, one fact stands out on the very first page
(981) of this study published in "Aids."1 The authors plainly state:
"Preliminary work has suggested that ozone does inactivate HIV in
vitro." Then they also state that they proved ozone does indeed kill
HIV-1. They withdrew 10cc's of blood, and interfaced 3 mcg/ml3 of
ozone with it, and the ozone destroyed all the HIV-1 viruses, and
didn't hurt the blood. "The resulting inoculation presents a killed
virus antigen preparation." These statements alone prove ozone
deserves further study!
Let's examine the materials and methods used. Here's a comparison of
the outdated protocols employed in the study and modern medical ozone
delivery methods:
1990 antiquated (MinAH) Standard private medical
Canadian study ozone protocol
------------------------------ ----------------------------------
-Treat outside body. -Inject directly into the vein,
or constant recirculation.
-Withdraw 10cc's of blood. -Inject/recirculate up to
500ccs, or whole blood supply.
-Treat with 3 mcg/ml3 -Minimum of 27 to 42 mcg/ml3
concentration. concentration.
-Ozone was heated. -Ozone never heated. Heat
destroys ozone.
-Injected into huge gluteus -Always infused into
maximus muscle. veins/arteries.
-Injected only three times -Best applied once or twice
per week. per day.
Also
Ignored results. The published document ignored the results of Phase
1A wherein 3 of the few patients who had any immune system left - each
with CD4 T-cells above 200 - had their counts go from 220-230 up to
500. The patients gained weight, and reported feeling great. Instead,
the published document stated: "no difference was seen between placebo
and ozone treated patients." Reason: I learned from a personal
interview with the ozone generator manufacturer's technician that in
Phase 1B, the second half of the study, either the ozone generator
mysteriously "broke," or someone deliberately sabotaged it, because
The ozone generator was producing very little or no ozone! and when
the Meuller medical technician dutifully reported this to the
investigators, he and this fact were ignored, and the study was
written up without reflecting the facts!
Incorrect dosage schedules and volumes. Phase 1A and Phase 1B treated
only 10cc's of patient blood on only three times a week treatment
days.
Wrong procedure. This is fine to make an inoculation, but inoculations
only work on people whose immune system are fully functional,
certainly innoculations are not applicable to a study of AIDS patients
and their compromised immune systems with only 50 to 500 T cell count
ranges.
Ozone is used to sterilize municipal drinking water all over the
world. How are you going to clean up the microbe infested waters that
the human patients are made up of, by putting only 10cc's (less than a
teaspoon) of barely touched with ozone blood into a muscle - and only
three times a week?
Compare this choice of minor autohemotherapy (MinAH), with its only
thrice weekly injections against the obvious objective of getting rid
of this disease by cleaning all the viruses, bacteria, funguses, and
parasites out of the 100 POUNDS+- of water that the human body
consists of. The injected small amount of oxygen/ozone is used up when
the oxygen tries to oxidize the existing and incoming pollution and
microbes. The total cleansing objective is challenged daily by the
added burden of leaving 2 1/3rd days of normal daily living between
treatments. This skipping treatment days allows the environmental and
dietary toxic intake load to continually tend to undo this miniscule
attempt at the cleaning process. There is no way you could ever hope
to "keep up" with this method by cleaning faster than the body absorbs
new toxic burdens, especially under the stress of a disease like AIDS
and its constant bacterial and viral replications! 10cc's of minor
autohemotherapy is to be considered only a drop in the pond of the
diseased body waters.
Incorrect concentrations. The tiny 10cc's of withdrawn patient blood
was treated with an equally tiny 3 microgram per cubic millimeter by
weight, ozone concentration (assuming a functioning ozone generator).
Private clinics using ozone know that a minimum of 27 to 42 mcg/ml3
concentration is necessary for maximum viral kill with a minimum of
hemolysis (Standard acceptable levels of normal cell damage). This
study used only a drop in the pond of acceptable concentrations.
Wrong delivery method. The tiny amount of blood with the (possibly
intermittent or non-existent) tiny concentration of ozone was
introduced into the body by injecting it into a large muscle. No-one
who really knows how to use ozone has employed this method since 1938,
when Dr. Paul Aubourg used it in his study in two Paris hospitals. He
proved that although other methods of the application of ozone, like
rectal insufflation, gave excellent effectiveness, the intramuscular
injection method was "painful and ineffective." (5)
The actual data does not match the published conclusions. Even more
suspect than the above errors is a detailed comparison between the
actual investigators' internal inter-office correspondence, and the
final published document. Let's look at excerpts from a letter by
Captain Michael Shannon, now Commodore Shannon of the Canadian
Department of National Defence (the Canadian military forces) written
to Dr. D.W. Boucher on January 24, 1990.
Note: A copy of the letter to Dr. Boucher and the accompanying data
was stamped CONFIDENTIAL and handed / leaked to me at a health show in
a plain brown envelope by an interested party who said, "You don't
know where you got this." The party was outraged at the following
duplicity, but too self-protective to directly challenge "the system."
Actually, there was no need of all the cloak and dagger stuff, because
a copy of the exact same letter - not marked confidential - had
previously been published by Barry Bruder in his work "Ozone
Therapeutics, A Current Compendium" in August of 1993.
M.E. Shannon CD,MA,MSC,MD one of the principal investigators wrote the
following in his final report and recommendations to the superior
official representing the government funding, Dr. D.W. Boucher, of the
Bureau of Biologics, Health Protection Branch, Health and Welfare,
Tunney's Pasture, Ottawa, Canada, on January 24th, 1990:
"Ozone Therapy In AIDS/Project #231 Summary of Findings."
Dr. Shannon:
This trial yielded... "encouraging results"
"There has been no clinical, biochemical or immunological evidence of
adverse/toxicological effects."
"An improved sense of well being characterized the clinical responses
of all patients..."
"...several patients reported a return of appetite and concomitant
weight gain."
"4 patients suffering from arthralgic pain reported a significant
amelioration of symptoms."
3 out of 4 "reporting complete relief of what was well documented to
have been a chronic condition."
"The lack of bruising at the site of injection was somewhat
surprising."
"Three patients showed a significant positive response..." in their
CD4 measures.
"There were no detrimental effects on absolute CD4 counts for any of
the patients."
"One patient showed a 52% reduction in the initial P24 antigen levels
with a corresponding increase in absolute CD4 count."
The earlier Sept to October 1989 series of investigations by Dr. M.O.
Shaughnessy at the Virology Division of the Bureau of Laboratories and
Research Services "clearly support the contention that the technology
has potent virucidal (virus inactivating) effects."
"It would appear that this form of therapy constitutes a potent means
of inactivating HIV-1 in contaminated blood supplies, and may also
provide a means for patient specific "autovaccination" in selected
cases." ("Selected cases" meaning those with enough of an immune
system left so that an innoculation will make the immune system
respond.)
"These results are considered well beyond the error limits for the
particular assays, and indicative of potential therapeutic benefits
which should be further investigated."
"As reported in earlier correspondence, (1988/89 Ottawa General/NDMC)
several cases of long standing sciatica and one case of severe facial
pain secondary to an invasive naso-pharyngeal carcinoma responded
dramatically to this form of therapy."
"As the understanding of ozone biochemistry increases and potential
toxicological concerns dissipate, analgesic applications of this
therapy should be pursued."
"Since a subgroup responded, consideration should be given to the need
for extended follow-up, and administration of a "booster cycle" to
commence as soon as possible."
DR. SHANNON'S RECOMMENDATIONS AFTER COMPILING THE TRIAL DATA
"The results of this Phase I clinical trial are sufficiently
encouraging that the research team at the Ottawa General Hospital
would like to pursue an extension to the subject trial as outlined..."
"The potential benefits of this inexpensive, safe, and possibly
efficacious treatment for the rapidly growing HIV-1 pandemic warrants
further attention. Your assistance in this regard is respectfully
solicited."
THE ACTUAL WRITTEN AND PUBLISHED PAPER
Remember, these two following statements are being quoted and passed
around by government agencies as "proof" that ozone "doesn't work."
1. "In summary, these small pilot studies have shown that the Meuller
Ozon-O-Med ozone therapy protocol appeared to have no detectable
beneficial effect."(?,!) (Emphasis mine.)
2. "Our work does not, therefore, support the continued use of this
technique in patients with HIV associated immune disease."(?,!)
(Emphasis mine.)
Even with all the problems this study had, they never said "ozone
doesn't work," only that the delivery method didn't work! So, if
someone or some agency tries to use this study as proof that ozone
doesn't work, they are blatently guilty of deception.
Although 5 investigators were listed as principals on the published
paper, exactly who were the actual final paper-writing authors? From
Dr. Shannon's communication to The Bureau of Biologics:
"Be advised that Dr.'s Garber and Cameron (Ottawa General Hospital)
have formally submitted an abstract related to this trial to the
International Conference on AIDS presentation this June."
It is also extremely interesting to further note that Dr. Shannon was
never given a review copy to sign off on before the paper was
published. In other words, although his name appears upon the
published version, he was denied any input into the final version of
what was said.
What forces would promulgate this obvious perversion of truth? One
source I interviewed, an enthusiast for Canadian ozone research,
stated that he understood "the word on the street" to be that Dr.
Garber was looking forward to proudly announcing the positive results
at the upcoming big AIDS conference, but when the second phase didn't
produce as good results as the first phase, he became crestfallen and
couldn't make the announcement. He turned his back on the project. Of
course, the non-existant daily quality checking of the ozone generator
was his responsibility. So then he either had to go on record
admitting that the trial he was responsible for was flawed, or
alternatively, make the claim ozone is worthless. History shows the
decision that was made.
There is another aspect that I attribute to no one person, but I
believe it must be considered as a possible shadowy, yet powerfull,
influence. Although it is shocking to any sane person to consider this
scenario, we must also ask ourselves ask who would financially loose
the most if AIDS and a host of other diseases, like cancer, etc., were
to actually be improved, cured, or at least treated back to a level of
remission? Hint. You wouldn't need huge AIDS specialized government
oversight agencies, and their supervisors, huge sums of private or
federal research funds, billions of dollars in drug sales yearly, or
healthcare workers, or hospitals, or grassroots AIDS groups, and their
directors, and their funding. That is, of course, unless all these
people and institutions were willing to clean up their lives, stop
"going along", and be directed into POSITIVE life affirming employment
and enterprises.
Was this influence at work when Dr. Shannon was seeking labs to
possibly continue the research, yet was told "All the labs are booked
up for years on other work."(8) Who would have enough money to tie up
all the labs and lock ozone out?
Why wouldn't Captain, now Commodore, Shannon come forward and publicly
withdraw his support of the study? Who can blame him, we all know
what happens to military "whistleblowers." Even though he hasn't
spoken out, he remains absolutely pro ozone to this day.(8)
Why would the investigators, and all the connected agencies, ignore,
and continue today to ignore, the notification of the broken machine?
Perhaps to have spent or taken the money to do such an expensive
study, and being known as a "respected department," or "respected
investigator" with a reputation to protect, and above all a need to
continue the funding, maybe it is just too hard to admit your people,
or you, personally, didn't do an expensive study correctly by
completing such a basic daily task as quality checking the ozone
producing machine. Let us hope that more nefarious forces were not in
play.
And finally, Why would the published data suddenly and mysteriously
change its obviously positive data into a negative published
summation?
Unfortunately, the stench from this rotting carcass now infests my
country as well. The U.S. FDA uses this same study as a reference, and
seriously oversteps the truth and their boundaries to make the
unjustified, and way too broad pronouncement that, based upon this
Canadian report, "Ozone therapy does not enhance parameters of immune
activation nor does it diminish measurable p24 antigen in HIV-infected
individuals." From an actual FDA letter to one of our elected U.S.
representatives, Congressman Sherwood Boehlert. Remember, the false
published paper clearly never says that ozone doesn't work, but that
only the particular delivery system of minor autohemotherapy, as used,
incorrectly, and with its broken generator, doesn't work. Quell
suprise!
I agree wholeheartedly that the protocols, as used here, are terribly
ineffectual when compared to normal medical ozone therapies as
practiced daily worldwide by thousands. Especially if you try it with
a faulty generator. Even with this handicap, the plain facts remain
that the investigators used a comparatively ineffectual ozone delivery
method, an antiquated protocol, and a possibly broken generator, to
create only a killed virus antigen preparation, and then injected too
little of this mixture in the wrong place. Even these inadequate
methods yielded such surprisingly positive results (when given time to
do their work in a few of the patients whose immune systems were still
functioning) that these amazing results had to be hidden from the
public.
So, in summary, a protocol that any serious practitioner would laugh
at was used, their conclusions were based upon false data - if the
machine was broken, and their fraudulent conclusions were written in
total disregard for human suffering, not caring how far back ozone
research would be set, or how many lives were at stake.
The tragedy of allowing such abberant summations to be published, and
to allow such pronouncements to be made based upon the mysterious
summations, is that this errant information is repeated by supposedly
impartial agency officials to our elected representatives and to news
reporters, while these very agencies ignore the thousands of studies
that show ozone does work(3,4.) This downright intellectual
dishonesty is used to politically justify barring further real
research into ozone in North America that would immediately prove we
have something ready right now to eliminate suffering and save lives.
We know this is true, because ozone has been in use for 100 years by
thousands of physicians. (2,3,4,5,6,7)
The miscarriage of justice and perversion of facts here is so
overwhelmingly evident that I don't know what more to say, but I will
say this:
Exactly what factors came into play in the minds of the authors, the
"reputable scientists" that we have trustingly given the care of
ourselves and our loved ones to, when they obfuscated the truth needed
by the sick and dying, so as to further delay the introduction of
ozone medical therapies in the U.S. and Canada? Why would any sane
person deny a very badly needed therapy to the sufferers of disease?
May God have mercy on their Souls, for they know not what they do when
men trade their honor for convenience.
Where are the positive thinking Canadians attempting to go from here?
Quoting Commodore Shannon:(8)
"Allister Clayton, the Director of the Federal Center for AIDS went
to bat for our funding."
"The book is not closed on the efficacy of ozone therapy for the
treatment of AIDS."
"We need more funding."
"There is a role for ozone in medicine."
In March/April of 1995 Medizone International from New York will be
announcing the results (which logically would be successful) of their
preliminary 300 patient HIV/Hepatitis ozone trials going on in Italy
under the auspices of several universities and The Italian Medical
Ozone Society.
In March/April 1995, Cornell University is expected to announce the
results of their ongoing ozone blood safety and sterilization trials.
References:
1. The Use of Ozone-Treated Blood in the Therapy of HIV Infection and
Immune Disease: A Pilot Study of Safety and Efficacy. AIDS 1991,
5:981-984
2. Safety - January 1980, The German Medical Society for Ozone
Therapy commissioned Marie Theresa Jacobs and Prof. Dr. Dr.
Hergetbegan from the University Kilnikum Giessen and the Institute
for Medical Statistics and Documentation of Giessen University to
begin an inquiry entitled "Adverse Effects and Typical
Complications In Ozone Therapy." 2,815 questionnaires were sent
out to all western German ozone therapists known by the Medical
Society for Ozone Therapy (AGO, Arztliche Gesellschaft fur
Ozontherapie). 884 went to physicians and 1931 to therapists.
They collected 1,044 replies, or 37% of the total. The replies
that were returned stated 384,775 patients were treated with ozone
with a minimum of 5,579,238 applications and the side effect rate
observed was only .000005 per application! The report also stated
"The majority of adverse effects were caused by ignorance about
ozone therapy (operator error)." The University of Innsbruck's
Forensic Institute published Dr. Zacob's dissertation quoting this
in The Empirical Medical Acts of Germany.
3. "Ozone Vs. AIDS, The history and suppression of ozone therapy in
the United States as of May 1994" Energy Publications 305/759-8710
(Referencing 120+ ozone medical references).
4. Get a computer with a modem, and get on the Internet, and write an
"email" message to majordomo@io.org On the first line
of the message, put SUBSCRIBE OXYTHERAPY-L if you wish to be on the
computer mailing list ozone discussion group. Worldwide Web users web to:
http://www.oxytherapy.com Or call 305/759-8710 to
order the proof.
5. "Medical Ozone: Production, Dosage, and Methods of Clinical
Application". Parisian Medical Bulletin - Bul Med Paris 52 or
42:745-749,
6. 1885 Florida Medical Association published "Ozone" by Charles J.
Kenworthy, M. D., M.R.S.V. from Jacksonville Florida. Dr.
Kenworthy was bubbling ozone through blood to sterilize it. This
proves that ozone was in regular medical usage in the U.S. before
1885, and therefore predates the 1906 Pure Food and Drug Act.
7. 1993 Sept 2, World premier of Canadian 1/2 hour video "Ozone and
The Politics of Medicine" by Geoff Rogers and Riener Diedrau at
the International Ozone Association meeting, San Francisco
California. Dr. Horst Kief from Germany states there are over
8,000 doctors using ozone in Germany and Austria alone today.
8. Cmdr. Shannon personal interview with Ed McCabe 12/19/94.