Ozone Plus Cobalt Therapy in Patients Suffering from Prostatic
L. Borrego, L. L. Borrero, E. C. Díaz(1), S. Menéndez(2), L. R.
Borrego(3), R. A. Borrego(3).
Provincial Center of Retinitis Pigmentosa, Holguín, Cuba.
1 – V.I. Provincial Center of Retinitis Pigmentosa, Holguín, Cuba.
2 – Ozone Research Center, Cuba.
3 – Faculty of Medicin, Holguín, Cuba.
Prostatic adenocarcinoma is the most frequent tumor in men older
than 50 years old, representing the 16.7 % of all the death cases
of cancer in male sex. With an early diagnose and an appropriate
treatment the survival increase in 5 years, in 91 % of cases.
Cancer metabolism is fundamentally anaerobic, for that reason,
increasing oxygenation in damaged tissues, may diminished the side
effects produced by radiation treatments, as well as increase
radio-sensibility. The aim of this study is to evaluate the
efficacy of ozone therapy in conjunction with cobalt-60 therapy,
in the treatment of patients suffering from prostatic cancer,
taking into account the influence that ozone exerts in tissue
oxygenation. 70 patients with malignant neoplasia in prostate,
stage A and B of the disease (intracapsular) were treated by an
oncourology muldisciplinary group of the “Lenin” Hospital (Holguin
Province). 35 patients were treated with rectal ozone plus cobalt
therapy (ozone group) and 35 with cobalt therapy only (control
group). The appearance of side effects (dermatitis radiation,
cystitis, proctitis) and the behavior of some humoral and clinical
parameters were evaluated up to 6 months after finishing the
treatment. 84 % and 52 % of side effects were presented in
control group and ozone group, respectively. Prostatic specific
antigen (PSA) decrease, less than 10 ng/mL, in 92 % of patients
treated with ozone and in 52 % in control group, one month after
finishing the treatment. 88 % and 80 % of clinical and humoral
control of the disease were obtained in ozone group and control
group, respectively, 6 months later. It is concluded that,
combining cobalt therapy with ozone, a decrease in side effects
and an increase in radio-sensibility were achieved.
Source: 2nd International Symposium on Ozone Applications
Havana, Cuba – Mach 24-26, 1997.